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Cornell Pediatrics

Published Research from Our Faculty

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IGFBP-1 to Screen for Insulin Resistance by R. Motaghedi et al
Sep. 13, 2007
 
 
News About Influenza B Drug Resistance That Cannot Be Ignored by Moscona, A. and McKimm-Breschkin, J.
Apr. 4, 2007
The emergence of drug-resistant influenza B should draw attention to the importance of continual monitoring of strains over time and to the need for frequent rethinking of policies for use of antiviral drugs.
 
A Second Receptor Binding Site on Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Contributes to Activation of the Fusion Mechanism
Jan. 17, 2007
The hemagglutinin-neuraminidase (HN) protein of paramyxoviruses carries out three discrete activities that affect the ability of HN to promote viral fusion and entry: receptor binding, receptor cleaving, and triggering of the fusion protein. The authors suggest that the two receptor binding sites on HPIV3 HN each contribute in distinct ways to virus-cell interaction; one is the multifunctional site that contains both binding and neuraminidase activities, and the other contains binding activity and also is involved in fusion promotion.
 
Niche-to-niche migration of bone-marrow-derived cells
Jan. 2, 2007
A summary of the current understanding of haematopoietic stem cell (HSC) niche characteristics, and the physiological and pathological mechanisms that guide HSC homing both within the bone marrow and to distant niches in the periphery, promoting new vessel growth in tumors and ischaemia.
 
A daring treatment and a successful outcome: The need for targeted therapies for pediatric respiratory viruses
Jan. 1, 2007
A team of dedicated physicians rely, successfully, on an untested treatment for their pediatric patient actively infected with human parainfluenza virus type 3 (HPIV3), highlighting the need for specific proven strategies to protect and treat children with this virus.
 
Preparing the "Soil": The Premetastatic Niche
Dec. 1, 2006
Focus on the early cellular and molecular events in cancer dissemination and selectivity will likely lead to new approaches to detect and prevent metastasis at its earliest inception.
 
Capsule Endoscopy Called Safe, Clinically Useful
Dec. 1, 2006
Dr. Robbyn Sockolow, Division Chief of Gastroenterology in the Department of Pediatrics at Weill Cornell, and her team conduct a study concluding that capsule endoscopy appears safe and effective for the diagnosis and management of children with gastrointestinal diseases.
 
Bone marrow cells in the 'pre-metastatic niche': within bone and beyond
Dec. 1, 2006
A discussion of the inextricable relationship between bone stromal components, metastasizing cells, and bone marrow-derived hematopoietic cells, and their roles in carcinogenesis and metastasis.
 
AMG 531, a Thrombopoiesis-Stimulating Protein for Chronic ITP
Oct. 19, 2006
AMG 531, a thrombopoiesis-stimulating protein, caused no major adverse events and increased platelet counts in patients with chronic immune thrombocytopenic purpura (ITP).

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