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Cornell Pediatrics

Published Research from Our Faculty

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Adalimumab therapy for childhood uveitis
Oct. 1, 2006
Research indicates that adalimumab may be a useful therapy for children with idiopathic and JIA-associated uveitis, though a larger placebo-controlled trial is required to conclusively demonstrate the efficacy of this therapy.
 
Inhibition of Hendra Virus Fusion
Oct. 1, 2006
Hendra virus (HeV) is a recently identified paramyxovirus that is fatal to humans. Researchers have found that a human parainfluenza virus 3F-peptide is more effective at inhibiting HeV fusion than the comparable HeV-derived peptide.
 
Evaluation of Short Stature, Carbohydrate Metabolism and Other Endocrinopathies in Bloom's Syndrome
Jun. 9, 2006
Altered carbohydrate metabolism is very common in Bloom's Syndrome, and is present from childhood. Bloom's Syndrome dwarfism is not related to growth hormone deficiency or malabsorption.
 
A Phase 3 Study of Deferasirox, a Once-Daily Oral Iron Chelator, in Patients with beta -Thalassemia
Jun. 8, 2006
Deferasirox is FDA approved as a once-daily oral iron chelator developed for the treatment of chronic iron overload from blood transfusions.
 
Oseltamivir Resistance - Disabling Our Influenza Defenses
Dec. 22, 2005
Research stresses the necessity of devising pandemic strategies that do not favor the development of oseltamivir-resistant strains. Improper use of personal stockpiles of oseltamivir may promote resistance, thereby lessening the efficacy of our frontline defense against influenza.
 
Blood Platelet Levels Significantly Increased with Eltrombopag, Global Study Shows
Dec. 12, 2005
Drug Shown to be Effective and Safe in Patients Suffering from Immune Thrombocytopenic Purpura (ITP), an Autoimmune Condition Resulting in Decreased Blood Platelets
 
Keeping Cancer from Fertile Ground: Weill Cornell Team Identifies Key Players in "Pre-Metastasis"
Dec. 7, 2005
Groundbreaking Work Could Lead to New Drug Targets and Methods of Assessing Cancer Recurrence Risk
 
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
Dec. 1, 2005
Research findings demonstrate a requirement for VEGFR1 haematopoietic progenitors in the regulation of metastasis, and suggest that expression patterns of fibronectin and VEGFR1 VLA-4 clusters dictate organ-specific tumour spread.

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