Infectious Disease Research
Research programs in the Division of Pediatric Infectious Diseases include: Molecular pathogenesis research (respiratory viruses, viral agents of bioterrorism, and host defenses) and clinical research projects.
Basic science research in the Program for Respiratory Infections (Dr. Moscona's laboratory) centers on molecular pathogenesis of human paramyxoviruses: parainfluenza virus, and the emerging pathogen Hendra virus. Parainfluenza virus is an important cause of lower respiratory tract infections in children, including croup and bronchiolitis, and there are currently no vaccines or antiviral agents for these diseases. Hendra virus is a highly fatal paramyxovirus which is a potential agent of bioterrorism. The Moscona laboratory studies how these viruses enter cells by fusing with the cells envelope, and in how we might interfere with this viral entry process and prevent or treat the diseases. Both the parainfluenza and Hendra virus projects are funded by investigator-initiated NIH grants. [More
about Dr. Moscona's research]
Clinical research in the Division focuses on molecular epidemiology of emerging resistance of bacteria to antibiotics, and translational and clinical research in Pediatric AIDS.
About Dr. DeLaMora's research
About Dr. Moscona's research
About Dr. Porotto's research